Responsable: Dra. Emma Elisa Ortiz Islas
5606 3822 ext. 5034
Objetivos:

Diseñar de materiales con tamaños a la escala nano-métrica (1-100 nm) para la liberación controlada de fármacos dentro del sistema nervioso central.

Formar recursos humanos a nivel licenciatura, maestría, doctorado y postdoctorado.

Líneas de investigación:
  • Diseño, preparación de materiales biocompatibles para su uso como sistemas de liberación de fármacos neurológicos y de agentes quimioterapéuticos.
Estudios de Ciencia Básica
  • Caracterización de nanomateriales con diversas técnicas fisicoquimicas para determinar sus propiedades morfológicas, estructurales y superficiales.
  • Biocompatibilidad de los materiales usando líneas celulares y ratas Wistar
  • Aplicación de los nanomateriales en modelos animales y líneas celulares.
Publicaciones más recientes y relevantes:
  • L-DOPA Stabilization on Sol-gel Silica to be used as Neurological Nanoreservoirs: Structural and Spectroscopic Studies. Tessy López, Dulce Esquivel, Guillermo Mendoza- Díaz, Emma Ortiz-Islas*, Richard D. González, Octavio Novaro. Materials Letters. 2015, 161:160–163.
  • Release of copper complexes from a nanostructured sol-gel titania for cáncer treatment. Tessy López, Emma Ortiz-Islas*, Patricia Guevara, Francisco Rodríguez-Reinoso, Esteban Gómez, José Luis Cuevas, Octavio Novaro. Journal of Materials Science. 50 (2015) 2410-2421.
  • Preparation and Characterization of Kynurenic Acid Occluded in Sol-Gel Silica and SBA-15 Silica as Release Reservoirs. Tessy López, Emma Ortiz*, Esteban Gómez, Verónica Pérez-de la Cruz, Paul Carrillo-Mora, Octavio Novaro. Journal of Nanomaterials. 2014 (2014) 1-8.
  • Physicochemical characterization of functionalized-nanostructured titania as a carrier of copper complexes for cancer treatment. Tessy López, Emma Ortiz*, Patricia Guevara, Esteban Gómez, Octavio Novaro. Materials Chemistry and Physics. 146 (2014) 37-49.
  • Occlusion of INTERFERON® and COPAXONE® on SBA-15 Silica Reservoirs for their Use in the Treatment of Demyelization Diseases. Tessy López, Emma Ortiz-Islas*, Miriam López, José Flores and Teresa Corona. Journal of Nanomaterials & Molecular Nanotechnology. 2013, 2:4.
  • Catalytic nanomedicine technology: copper complexes loaded on titania nanomaterials as cytotoxic agents of cancer cell. Tessy Lopez, Emma Ortiz-Islas*, Patricia Guevara, Esteban Gómez. International Journal of Nanomedicine. 2013:8 581–592.
  • Preparation and characterization of copper compounds co-gelled with nanostructured TiO2 materials to be used in cancer treatment. T. López, E. Ortiz-Islas*, P. Guevara and J.V. Rios. Science for Advanced Materials. 4(2012)579–583.
  • Treatment of Parkinson’s disease: Nanostructured sol-gel silica-dopamine reservoirs for controlled drug release in the central nervous system. Tessy López, José L Bata-García, Dulce Esquivel, Emma Ortiz-Islas, Richard Gonzalez, Jorge Ascencio, Patricia Quintana, Gerko Oskam, Fernando J Alvarez-Cervera, Francisco J Heredia-López, José L Góngora- Alfaro. International Journal of Nanomedicine. 6(2011)19-31.
  • Study of the stabilization of zinc phthalocyanine in sol-gel TiO2 for photodynamic therapy applications. Nanomedicine: Nanotechnology, Biology, and Medicine. T. Lopez, E. Ortiz, J. Navarrete, J. A. Odriozola, F. Martinez-Ortega, E. A. Páez-Mozo, Patricia Escobar, K. A. Espinoza, and I. A. Rivero. Nanomedicine: Nanotechnology, Biology and Medicine. 6(2010)777-785.
  • Release properties and acute biosecurity determination of collagen- polyvinylpyrrolidone loaded in ordered mesoporous silica. T. López, E. Krötzsch, E. Ortiz- Islas, M. Alvarez-Lemus, E. Balsadella, J.M. Martínez-Blanes and J.A. Odriozola. Key Engineering Materials. 391(2009)169-184.